Synthetic Route of 50548-45-3, The chemical industry reduces the impact on the environment during synthesis 50548-45-3, name is 1-Bromodibenzo[b,d]furan, I believe this compound will play a more active role in future production and life.
Under an argon atmosphere, 1.00 g of Compound B, 2.81of 1 -bromodibenzothran, 0.27 g of bis(dibenzylideneac5 etone)palladium(0), 0.088 g of tri-tert-butylphosphine and3.98 g of sodium tert-butoxide were added to a 500 ml, three necked flask, followed by heating and refluxing in 200 ml oftoluene solvent for about 7 hours. After air cooling the resulting reactant, water was added to the reactant, an organic layer was separated therefrom, and solvents were distilled. The crude product thus obtained was separated using silica gel column chromatography (using toluene/hexane) to produce 1.90 g of Compound C as a white solid(Yield 70%). The molecular weight of Compound C thusobtained was measured using FAB-MS, and a value of 525 (C38H23N02) was obtained. In addition, the glass transition temperature of Compound C was measured using a differential scaiming calorimetry (DSC 7020 of Hitachi HightechCo.) and a value of 120 C. was obtained.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Bromodibenzo[b,d]furan, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Samsung Display Co., Ltd.; Miyake, Hideo; Takada, Ichinori; Nakano, Hiromi; (31 pag.)US10347844; (2019); B2;,
Bromide – Wikipedia,
bromide – Wiktionary