Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3972-64-3, name is 1-Bromo-3-(tert-butyl)benzene, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 1-Bromo-3-(tert-butyl)benzene
A 1.7 M solution of tert-butyllithium in pentane (2.60 mL, 4.42 mmol) was added to a solution of 1-bromo-3-tert-butyl-benzene (426 mg, 2.00 mmol) in tetrahydrofuran (5 mL) at-78 ¡ãC. After stirring for 1 h, tributyltin chloride (0.57 mL, 2.10 mmol) was added at-78 ¡ãC. After stirring for 18 h, during which time the solution warmed to ambient temperature, the solution was diluted with water and extracted with methylene chloride. The combined organic extracts were dried over magnesium sulfate, filtered, and concentrated to yield 976 mg (115percent yield) of tributyl- (3-tert-butyl-phenyl)-stannane as a impure light yellow oil.
According to the analysis of related databases, 3972-64-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ELAN PHARMACEUTICALS, INC.; WO2005/87215; (2005); A1;,
Bromide – Wikipedia,
bromide – Wiktionary