Reference of 65896-11-9,Some common heterocyclic compound, 65896-11-9, name is 2-Bromo-6-fluoroaniline, molecular formula is C6H5BrFN, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Example 2A Methyl (2E)-3-[2-amino-3-fluorophenyl]propenoate Starting with 42.00 g (221.04 mmol) of 2-bromo-6-fluoroaniline, the general procedure [B] gives 29.66 g (68% of theory) of product. HPLC (method 1): Rt=4.14 min MS (ESIpos): m/z=196 (M+H)+
The synthetic route of 65896-11-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Bayer HealthCare AG; US2007/185121; (2007); A1;,
Bromide – Wikipedia,
bromide – Wiktionary