Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 586-61-8, name is 1-Bromo-4-isopropylbenzene, A new synthetic method of this compound is introduced below., Product Details of 586-61-8
Under nitrogen conditions, o-aminobiphenyl (10.0 g, 59 l) was added to the reaction vessel,1-bromo-4′-isopropylbenzene (11.77 g, 59.1 mmol), tris (dibenzylideneacetone) dipalladium (0 ¡¤ lg), tri-tert-butylphosphine (15%, 0.3 g) (1.8 g) and toluene (300 mL) at 60 C for 12 hours. After the reaction solution was cooled, the silica gel filter was filtered and the solution was concentrated and subjected to column chromatography after dichloromethane and hexane to give Compound F-18 (11.50 g, yield 68%).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Jilin Aolaide Optoelectric Materials Co., Ltd.; Qin Cuiying; Yu Danyang; Sun Feng; He Jinxin; Wang Shikai; Jin Furong; (19 pag.)CN107162916; (2017); A;,
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