Application of 2635-13-4, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2635-13-4 as follows.
201mg (1mmol) of 3,4-methylenedioxybromobenzene, 1mL aqueous ammonia (25-28%, 13.3mmol), 8mg (0.1mmol) CuO, 79mg (0.2mmol) diethylenetriaminepentaacetic acid, 112mg ( 2mmol) KOH, 1mL H2O was added 10mL reaction tube, sealed and reacted at 100C for 12h. After the reaction was stopped, extraction with ethyl acetate, washed with brine, dried over anhydrous sodium sulfate, filtered, and the filtrate was evaporated under reduced pressure, purified by silica gel column chromatography purification, in 3,4-methylenedioxyaniline 100mg, The yield was 73%.
According to the analysis of related databases, 2635-13-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Sun Yat-Sen University; ZHU, XIN HAI; YANG, BO; LIAO, LI HAO; CENG, YONG HENG; WAN, YI QIAN; (9 pag.)CN103739417; (2016); B;,
Bromide – Wikipedia,
bromide – Wiktionary