Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 64695-79-0, name is 2-Bromo-4,5-difluoroaniline, This compound has unique chemical properties. The synthetic route is as follows., Formula: C6H4BrF2N
To a solution of 2-bromo-4,5- difluoroaniline (1.2 g, 4.3 mmol) in DMF (4 mL) was added tetrakis(triphenylphosphine)palladium(0) (400 mg, 0.34 mmol) and zinc cyanide (800 mg, 6.8 mmol). The solution was sparged with nitrogen and heated at 120 C for 30 minutes in a Biotage microwave reactor. The resulting suspension was filtered and concentrated in vacuo to afford the crude product. Purification by column chromatography (CI 8 reverse phase, water + 0.1% NH3 H20 -> MeCN + 0.1% NH3 H2O) afforded the desired 2-Amino-4,5-difluorobenzonitrile.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 64695-79-0.
Reference:
Patent; INCEPTION 1, INC.; JACINTHO, Jason, Duarte; CLARK, Ryan, Christopher; SHENG, Tao; OBALLA, Renata, Marcella; STOCK, Nicholas, Simon; ROPPE, Jeffrey, Roger; (161 pag.)WO2017/192304; (2017); A1;,
Bromide – Wikipedia,
bromide – Wiktionary