402-43-7, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 402-43-7 as follows.
General procedure: Na2CO3 (212 mg, 2 mmol), 4-chloronitrobenzene (1 mmol) and styrene (1.5 mmol) were added successively into a dried Schlenk tube under nitrogen. Then the DMA (0.1 mL) solution of DADPP (0.002 mmol) and [Pd(C3H5)Cl]2 (0.0005 mmol), which was reacted at 100 C for 10 min prior to use, was added into the mixture. The reaction was performed at 130 C. At the end of reaction, the mixture solution was extracted with ethyl acetate (3 ¡Á 5 mL). Combined organic phase was washed with brine (3 ¡Á 5 mL) and dried over MgSO4. The dried solution was filtered and purified with silica gel chromatography (petroleum ether 60-90 C) to give a corresponding product.
According to the analysis of related databases, 402-43-7, the application of this compound in the production field has become more and more popular.
Reference:
Article; Jiang, Zhi-Jie; Wang, Wei; Zhou, Rong; Zhang, Lei; Fu, Hai-Yan; Zheng, Xue-Li; Chen, Hua; Li, Rui-Xiang; Catalysis Communications; vol. 57; (2014); p. 14 – 18;,
Bromide – Wikipedia,
bromide – Wiktionary