In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 955959-84-9, name is 4-(4-Bromophenyl)dibenzo[b,d]furan belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. 955959-84-9
In the argon atmosphere, weighing intermediate respectively (1-1) 3.2g (10.0mmol), intermediate (A-2-1) 5.8g (10.0mmol), Pd2(dba)30.14g (0.15mmol), P (tBu)3HBF40.087g (0.3mmol), tertiary butyl alcohol sodium 1.9g (20.0mmol), adding anhydrous xylene 50 ml, heating reflux for 8 hours.After the reaction, the reaction mixture is cooled to 50 ¡ãC, filtered through diatomaceous earth/silica gel, concentrated filtrate. The obtained concentrated residue after being refined with silica gel column chromatography, using toluene recrystallization, get 2.9g of the white crystal (yield 35percent).
The synthetic route of 955959-84-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Idemitsu Kosan Co., Ltd.; Jiateng, Pengxi; Sounei, Shenhao; Zhou, Qiaozhenghe; Tengshan, Gaoguang; (107 pag.)CN105431417; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary