The chemical industry reduces the impact on the environment during synthesis 39478-78-9, name is 5-Bromo-2-methylaniline, I believe this compound will play a more active role in future production and life. 39478-78-9
The compound 5-bromo-2-methylaniline (3.0g, 16.1mmol),Alpha-bromocyclopropanone (2.9 g, 17.7 mmol) and N,N-diisopropylethylamine (4.2 g, 32.2 mmol) were dissolved in 100 ml of toluene and reacted at 100C for 15 hours.After the reaction is over, the reaction solution is concentrated,The residue was subjected to silica gel column chromatography (ethyl acetate: petroleum ether = 1:30) to obtain 3.37g of product,The yield was 78.4%.
The chemical industry reduces the impact on the environment during synthesis 39478-78-9. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Shandong Xuanzhu Pharmaceutical Technology Co., Ltd.; Wang Tingzhong; Liu Bin; (33 pag.)CN111170995; (2020); A;,
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