49764-63-8, Adding a certain compound to certain chemical reactions, such as: 49764-63-8, name is 4,5-Dibromobenzene-1,2-diamine, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 49764-63-8.
General procedure: Intermediate1 (3.17 g, 8.7 mmol) and 4,5-dibromobenzene-1,2-diamine (3.02 g, 11.35 mmol) were dissolved in 90 mL acetic acid,and then heated to reflux for 16 h. After cooling down, the resultingmixture was poured into water and neutralized by sodium hydroxide.The suspension was extracted with chloroform(50 mL 3), and the combined organic layer was washed withwater and dried over anhydrous sodium sulfate. After that, thesolvent was removed by vacuum distillation and the rest solid waspurified with a silica gel column. Using dichloromethane/methanol(v/v) 20:1 as eluent and gave the target compound as light yellowsolid (4.3 g, yield: 83%).
According to the analysis of related databases, 49764-63-8, the application of this compound in the production field has become more and more popular.
Reference:
Article; Yin, Xiaojun; Sun, Hengda; Zeng, Weixuan; Xiang, Yepeng; Zhou, Tao; Ma, Dongge; Yang, Chuluo; Organic electronics; vol. 37; (2016); p. 439 – 447;,
Bromide – Wikipedia,
bromide – Wiktionary