16518-62-0, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 16518-62-0, name is 3-Bromo-N,N-dimethylaniline, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: Boronic acid, aryl halide, Pd(dppf)Cl2*DCM, CsF, and dry dimethoxyethane (DME) were introduced in a 100 mL shlenk tube. The reaction mixture was flushed three times by vacuum/argon andstirred at 80 ¡ãC overnight. The reaction mixture was filtered through celite and rinsed with EtOAc. The solvent was removed under vacuum and the residue was purified by flash column chromatography (EtOAc-hexane).
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Reference:
Article; Roy, Pierre-Philippe; D’Souza, Kenneth; Cuperlovic-Culf, Miroslava; Kienesberger, Petra C.; Touaibia, Mohamed; European Journal of Medicinal Chemistry; vol. 118; (2016); p. 290 – 298;,
Bromide – Wikipedia,
bromide – Wiktionary