39478-78-9, Adding some certain compound to certain chemical reactions, such as: 39478-78-9, name is 5-Bromo-2-methylaniline, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 39478-78-9.
General procedure: In a typical run, h-BN(at)Fur(at)Pd(OAc)2 (0.05 mmol) was added to a mixture of arylboronic acid 1 (1.0 mmol), aryl bromide 2 (1.5 mmol) and K2CO3 (1.5 mmol) in water (1 mL). The resulting mixture was stirred at 70 C under Ar protection, and the progress of the reaction was monitored by TLC. After completion of the reaction, ethyl acetate was added to the reaction mixture and the catalyst was separated. The organic phase was washed with water, dried over anhydrous Na2SO4 and the solvent was evaporated under reduced pressure. Finally, the residue was isolated by chromatography on a column of silica gel to afford the corresponding product 3.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 39478-78-9.
Reference:
Article; Li, Weijian; Lv, Guanghui; Cheng, Xu; Sang, Rui; Ma, Xiaojun; Zhang, Yong; Nie, Ruifang; Li, Jie; Guan, Mei; Wu, Yong; Tetrahedron; vol. 72; 52; (2016); p. 8557 – 8564;,
Bromide – Wikipedia,
bromide – Wiktionary